County Agricultural Commissioners may adopt supplemental pesticide regulations with the approval of the ________.

The correct answer is the Department of Pesticide Regulation (DPR). County Agricultural Commissioners have the authority to adopt supplemental pesticide regulations to address specific local conditions or concerns. However, this authority is not unchecked; it requires the approval of the Department of Pesticide Regulation.

The DPR oversees pesticide use in California and ensures that state regulations align with both agricultural practices and environmental safety standards. By requiring the approval of the DPR, the system helps maintain consistency and ensures that county regulations do not conflict with statewide laws and policies, promoting a unified approach to pesticide management across the state. This oversight is essential for protecting human health, environmental quality, and agricultural productivity.

The other options, such as local government, the Environmental Protection Agency (EPA), and the Department of Environmental Health, do not play a direct role in the approval process for these specific supplemental pesticide regulations. The local government may have its own regulations or permits but does not have authority over pesticide regulations. The EPA oversees federal pesticide laws, while the Department of Environmental Health deals with public health concerns but does not directly approve pesticide regulations at the county level.