If an employee works more than 6 days in a consecutive 30-day period with organophosphate or carbamate pesticides, what enzyme's blood levels must be monitored by a physician?

Monitoring cholinesterase levels in workers who are exposed to organophosphate or carbamate pesticides is crucial due to the way these substances affect the nervous system. Organophosphates and carbamates inhibit cholinesterase, an enzyme responsible for breaking down acetylcholine, a neurotransmitter. This inhibition can lead to an accumulation of acetylcholine, resulting in overstimulation of the nervous system, which can cause a range of symptoms from mild to severe toxicity.

When employees work with these pesticides, their exposure can lead to a significant decrease in cholinesterase levels, indicating potential poisoning. Therefore, health protocols mandate regular monitoring of this enzyme in individuals who have prolonged or high-level exposure, particularly after more than six days within a 30-day period. Should cholinesterase levels drop below a safe threshold, it serves as both a diagnostic indicator and a preventive measure, allowing for timely medical intervention to mitigate the effects of pesticide exposure.

The other enzymes listed do not provide relevant information regarding the specific neurotoxic effects associated with organophosphate and carbamate pesticides, making cholinesterase the critical marker for monitoring in this context.