Which government entity is primarily responsible for pesticide safety regulations?

The Department of Pesticide Regulation is primarily responsible for pesticide safety regulations at the state level. This entity specifically manages and enforces the use of pesticides to ensure they are applied safely and effectively while protecting human health and the environment. The Department of Pesticide Regulation oversees the registration of pesticide products, licensing of pest control businesses, and the enforcement of regulations that govern pesticide use.

While other agencies, such as the Environmental Protection Agency, also play a significant role in setting national standards and regulations for pesticide safety, the Department of Pesticide Regulation focuses on local implementation and enforcement, ensuring that state-specific laws and guidelines are properly adhered to. This distinction makes it the correct answer in this context, as the question asks for the government entity primarily responsible for pesticide safety regulations.